Cancer-related fatigue (CRF) is a common and relevant symptom in patients with advanced cancer that significantly decreases their quality of life.

Fatigue associated with cancer has a complex aetiology. It results from the interaction of 2 factors: those related to the disease itself or its treatment, and reduced physical activity. For this reason, the treatment of CRF should be multi-faceted and include, among others, physiotherapy. The maintenance of physical activity plays an important role in the treatment of fatigue.

The aim of this RCT was to evaluate the effect of a physiotherapy programme on CRF and other symptoms in patients diagnosed with advanced cancer and receiving palliative care.