A growing body of evidence exists, supporting the long term consequences of acute joint injury on the development of osteoarthritis (OA).

The following study examined the inherent risk of common knee pathologies have on the development of end stage OA resulting in total knee replacement (TKR).

The authors found a 7-fold and 15-fold increase in odds of individuals needing a TKR from OA compared to age and sex matched controls from ACL and meniscal injuries, respectively.