Altogether, this review shows McKenzie’s Mechanical Diagnosis and Therapy (MDT) method is not superior to a combined exercise and manual therapy approach for pain and disability in acute (

On the other hand, MDT showed greater effectiveness for the management of pain and disability in chronic (>12 weeks) LBP.

However, effect sizes were small to moderate and depending on the treatment being compared to MDT. Thus, a definite conclusion on the clinical significance of these diferences is still not possible.