The researchers of this article utilize an exercise program during neoadjuvant chemoradiotherapy (NACRT) to investigate if this improved cardiovascular function, quality of life, treatment response and possibly survival rate and reduced surgical complications.
For this study, 60 participants with colorectal cancer will be selected, who are going for NACRT before they have surgical resections of the tumour and bowel. They will be randomly assigned into a treatment or control group, with the treatment group engaging in high intensity interval training (HIIT) 3 times a week, as well as engaging in 150 minutes or more of unsupervised and moderate to vigorous continuous exercise after the completion of NACRT to surgery. The control group will be asked not to increase their exercise from baseline.
Outcome measures are both subjective and objective, including Quality of Life outcome measures by European Organisation of Research and Treatment of Cancer, VO2 max testing at the end of the program, functional fitness assessed by the Senior’s Fitness Test and symptom management assessed by a medical doctor.